Daptomycin rapidly penetrates a Staphylococcus epidermidis biofilm.
نویسندگان
چکیده
Fluorescently tagged daptomycin accessed the interior of Staphylococcus epidermidis biofilm cell clusters within minutes. The diffusion coefficient of daptomycin in the biofilm was 28% of its value in pure water. Daptomycin activity against staphylococci embedded in biofilms is unlikely to be limited by penetration of the antibiotic into the biofilm.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 53 8 شماره
صفحات -
تاریخ انتشار 2009